OneCareAI is born, the new spin-off of Barcelona Supercomputing Center (BSC) that will revolutionize stroke prevention with artificial intelligence.
Predict. Prevent. Protect. Progressing healthcare with AI
- OneCareAI, a spinoff initially conceived within the European AI-SPRINT project and now propelled by Innostroke, leverages artificial intelligence and high-performance computing to identify early stroke risk using electrocardiogram data captured by smartwatches.
- Beyond stroke detection, the technology shows promise for broader applications in cardiovascular, metabolic, and respiratory diseases. Its potential market spans hospitals, insurance providers, medical device companies, and telemedicine platforms.
Barcelona, April 20, 2025 – The Barcelona Supercomputing Center (BSC) has launched a new spinoff, OneCareAI, focused on the real-time, early, and personalized detection of cerebrovascular disease risk. This initiative stems from technology developed as part of the Innostroke project, fulfilling one of its core goals: the successful transfer of scientific innovation to the marketplace.
Innostroke is a project funded by the Recovery, Transformation and Resilience Plan, and is part of the National Artificial Intelligence Strategy (ENIA) and the
Knowledge Industry program, promoted by the Department of Research and Universities of the Generalitat de Catalunya. With the launch of OneCareAI, the BSC reinforces its commitment to innovation in digital health, offering a solution that brings the benefits of supercomputing and artificial intelligence to everyday life, with the aim of improving prevention and well-being.
OneCareAI was born from the need to transfer Innostroke technology, developed by computer and life science researchers at BSC, and initiated within the European
AI-Sprint project. Promoted by the Mobile World Capital (MWC) Foundation’s The Collider program, the spinoff has received support from national grants such as Innostroke and from the Product and Innovator modalities of the Knowledge Industry program, promoted by the Department of Research and Universities of the Generalitat of Catalonia.
The technology behind OneCareAI relies on electrocardiogram (ECG) data collected from wearable devices like smartwatches and integrates lifestyle information through a mobile app. This combination offers a non-invasive, accurate, and accessible solution that enables hospitals, insurers, and telemedicine providers to assess stroke risk with enhanced reliability and precision. Its innovative approach lies in the unprecedented integration of multi-omics data with ECG signals, significantly improving accuracy over traditional risk assessment methods, which often face major limitations.
“The launch of OneCareAI marks a pivotal milestone in translating Innostroke technology into real-world applications,” says Daniele Lezzi, co-founder of OneCareAI, senior researcher in the Department of Computer Science, and lead developer of the Innostroke technology since its inception. “This solution is the result of advanced work in supercomputing and artificial intelligence.”
Unlike existing systems, OneCareAI uniquely combines multi-omics data with ECG patterns to deliver far more comprehensive and precise risk evaluations. Additionally, its device-agnostic design ensures seamless compatibility with a wide range of commercially available wearables.
OneCareAI’s target market includes hospitals seeking improved patient monitoring and care, insurance companies aiming to enhance risk stratification, medical device manufacturers looking to integrate predictive features into their products, and telemedicine platforms seeking to automate diagnostic workflows. The business model is based on B2B subscriptions and co-development agreements with key players in the healthcare sector.
While its initial focus is stroke prevention, OneCareAI’s technology is designed to scale, with promising applications in the detection and management of other conditions such as cardiovascular, metabolic, and respiratory diseases.
“OneCareAI represents a new paradigm in medical prevention,” adds Davide Cirillo, co-founder of OneCareAI and head of the Machine Learning for Biomedical Research unit in the BSC Life Sciences Department. “It bridges science, technology, and personal well-being to anticipate cerebrovascular risks and enhance people’s quality of life.”

From scientific knowledge to a real impact on society
This initiative reflects one of the center’s key commitments: ensuring that scientific knowledge generates a real impact on society. OneCareAI contributes to strengthening strategic sectors such as digital health and disease prevention, to improve quality of life and collective well-being.
Although the prototype developed within the OneCareAI framework is still in the testing, development, and technological validation phase, it will be presented at two key conferences in the innovation ecosystem: in the startup pavilion at the IoT Solutions World Congress and at the Health Revolution Congress. Both events will be held in mid-May in Barcelona.
Thanks to both researchers’ participation in the Innovation Journey —a BSC training program that exposes entrepreneurial researchers to new market opportunities for their scientific projects or initiatives—as well as the support of national grants such as Innostroke and local grants, the transfer of this technology to the market has been boosted. Innostroke represents a good example of how the BSC promotes the transfer of knowledge and technology to the market, following a correct and well-structured process that can be considered a model for future initiatives.

The fourteenth spinoff of the BSC
With this new spin-off, OneCareAI becomes the fourteenth spin-off promoted by the BSC in its 20-year history. This reflects the center’s firm commitment to transforming scientific knowledge into real impact for society. The 13 previous spin-offs employ more than 380 highly qualified professionals and have successfully raised more than €40 million in private investment, consolidating an innovative ecosystem with significant potential.
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The Innostroke – Innovative Stroke Risk Monitoring with AI project has been funded by the Ministry of Digital Transformation and Public Service within the framework of the 2024 Artificial Intelligence Strategy and the Recovery, Transformation and Resilience Plan – funded by the European Union – NextGenerationEU .

The OneCareAI project has received funding from the Knowledge Industry program, Modality B for Products and Modality C for Innovators, awarded by the Agency for the Management of University and Research Grants (AGAUR) of the Generalitat of Catalonia.